5. Fibrocystic Breast Disease
While this one doesn’t necessarily relate to coffee on an empty stomach, it’s essential all the same. The Journal of the National Cancer Institute has reported a connection between caffeine consumption and fibrocystic breast disease (FBD).
If you drink between 31 and 250mg of caffeine every day, you had a 1.5-fold increase in the risk of getting the condition, or 2.3-fold if you drank over 500mg.